Pharmacological potential of Thymus serpyllum L. (wild thyme) extracts and essential oil: A review

In traditional medicine Thymus serpyllum L. (wild thyme) herb represents a part of large number herbal medicinal formulations such as syrups, tinctures, infusions, teas, and decoctions. recent years, there has been growing interest in testing the biological properties wild thyme, because plant is high-quality raw material, rich essential oil pharmacologically active polyphenolic compounds, which can be included various pharmaceutical, cosmetic, food, chemical industries. Wild thyme extracts have shown significant nitric oxide, ABTS DPPH radicals scavenging potential, ferrous ion chelating property, reducing activity ability to inhibit peroxidation deoxyribonucleic acid (DNA), proteins lipids. exerted antibacterial against Bacillus cereus, Enterococcus faecalis, Listeria monocytogenes, Staphylococcus aureus, Escherichia coli, Salmonella enterica, Yersinia enterocolitica, well Lactic bacteria. potential E. P. aeruginosa, S. enteritidis, Streptococcus salivariu, mutans, sanguinis, pyogenes, feacalis, B. subtilis, pumilis, Lactobacillus acidophilus, Proteus mirabilis, Klebsiella pneumoniae, choleraesuis, poona. T. extract possesses antifungal Fusarium solani, F. moniliforme, Aspergillus flavus, Microsporum canis, Alternaria species, Candida albicans, C. glabarata. The efficiently inhibited growth glabrata fungi. Depending on concentration, significantly relaxed spontaneous contractions, acetylcholine-, potassium chloride-, barium chlorideand calcium chloride-induced contractions isolated rat ileum. reduced expression inducible enzyme cyclooxygenase-2 acetylcholinesterase, myeloperoxidase α-glucosidase activity. cytotoxic human breast cancer cell lines, while antitumor lung cancer, colon, cervical, hepatocellular, prostate, adeno-carcinoma.